Is damage in central nervous system due to inflammation?

A Chavarria, J Alcocer-Varela - Autoimmunity reviews, 2004 - Elsevier
The aim of this work was to review the inflammatory factors involved in central nervous
system (CNS) inflammation and the damage associated to their participation in an …

Expression, purification, and characterization of rat interferon-β, and preparation of an N-terminally PEGylated form with improved pharmacokinetic parameters

RM Arduini, Z Li, A Rapoza, R Gronke, DM Hess… - Protein expression and …, 2004 - Elsevier
To identify potential new clinical uses and routes of administration for human interferon-β-1a
(IFN-β-1a), we have developed an expression and purification procedure for the preparation …

The potential pathogenetic link between peripheral immune activation and the central innate immune response in neuropsychiatric systemic lupus erythematosus

M Tomita, RL Khan, BH Blehm, TJ Santoro - Medical hypotheses, 2004 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology.
Neuropsychiatric disturbances unexplained by drugs or by other untoward manifestations of …