Separation methods of quinonoid constituents of plants used in Oriental traditional medicines

B Hazra, MD Sarma, U Sanyal - Journal of Chromatography B, 2004 - Elsevier
Analysis of molecular constituents of traditional Oriental medicines has acquired a fresh
perspective in view of a surge in interest in the consumption of herbal prescriptions all over …

Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor α promoter in vivo

V Staniforth, SY Wang, LF Shyur, NS Yang - Journal of Biological Chemistry, 2004 - ASBMB
Tumor necrosis factor α (TNF-α) contributes to the pathogenesis of both acute and chronic
inflammatory diseases and has been a target for the development of new anti-inflammatory …

[PDF][PDF] Chemokines and chemokine receptors as novel therapeutic targets in rheumatoid arthritis (RA): inhibitory effects of traditional Chinese medicinal components

X Chen, JJ Oppenheim, OM Howard - Cell Mol Immunol, 2004 - academia.edu
Chemokines are chemoattractant cytokines that direct the migration of leukocytes, and are
induced by inflammatory cytokines, growth factors and pathogenic stimuli (1). Chemokines …

Shiunko promotes epithelization of wounded skin

KF Huang, YC Hsu, CN Lin, JI Tzeng… - The American Journal …, 2004 - World Scientific
Shiunko is a traditional botanic formula (ointment) which is used clinically for the treatment of
wounded skin caused by cuts, abrasions, frost or burn. The aim of this study was to evaluate …

New advances in HIV entry inhibitors development

S Rusconi, A Scozzafava… - Current Drug Targets …, 2004 - ingentaconnect.com
Considerable advances have been made in the last years in the design of derivatives acting
as inhibitors of HIV entry and fusion. The discovery of chemokines focused the attention on …

Immunomodulatory effect of shikonin derivatives isolated from Lithospermum canescens on cellular and humoral immunity in Balb/c mice

A Pietrosiuk, E Skopińska-Różewska… - Die Pharmazie-An …, 2004 - ingentaconnect.com
The immunomodulatory activity of acetylshikonin (ACS) and isobutyrylshikonin (IBS) was
studied in female and male inbred Balb/c mice, and in F1 hybrids (Balb/c× C3H). ACS and …

Antiplatelet and antithrombotic activities of CP201, a newly synthesized 1, 4-naphthoquinone derivative

YR Jin, KA Hwang, MR Cho, SY Kim, JH Kim… - Vascular …, 2004 - Elsevier
The antiplatelet and antithrombotic activities of a newly synthesized CP201, 2-(3, 5-di-tert-
butyl-4-hydroxyl)-3-chloro-1, 4-naphthoquinone on human platelet aggregation in vitro and …

[引用][C] Antiplatelet activity of J78, an antithrombotic agent, is mediated by TXA2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ …

YR Jin, MR Cho, CK Ryu, JH Chung, DY Yuk… - … of Pharmacology and …, 2004 - ASPET
Platelet aggregation plays an important role in both physiological haemostatic and
pathological thrombotic processes. Once vascular injury occurs, platelets will be activated by …