Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A2 occurs predominantly during the secretory …
CM Mounier, F Ghomashchi, MR Lindsay… - Journal of Biological …, 2004 - ASBMB
Stable expression of human groups IIA and X secreted phospholipases A 2 (hGIIA and hGX)
in CHO-K1 and HEK293 cells leads to serum-and interleukin-1β-promoted arachidonate …
in CHO-K1 and HEK293 cells leads to serum-and interleukin-1β-promoted arachidonate …
p38 MAP kinase regulates rapid matrix metalloproteinase-9 release from eosinophils
S Wiehler, SL Cuvelier, S Chakrabarti… - … and biophysical research …, 2004 - Elsevier
Eosinophils constitutively produce and store matrix metalloproteinase-9 (MMP-9), a
protease implicated in tissue remodeling observed in asthma. In this study, we examined the …
protease implicated in tissue remodeling observed in asthma. In this study, we examined the …
β2-Integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and β2-adrenoceptor activation in human eosinophils
J Liu, NM Muñoz, AY Meliton, X Zhu… - Pulmonary …, 2004 - Elsevier
We investigated the effect and mechanism (s) of PDE-4 treatment with concurrent β2-
adrenoceptor stimulation on human eosinophil adhesion mediated by β2-integrin in vitro …
adrenoceptor stimulation on human eosinophil adhesion mediated by β2-integrin in vitro …
Inhibitor of p42/44 mitogen-activated protein kinase, but not p38 MAPK, attenuated antigen challenge of guinea pig airways in vitro
SC Chue, CJ Seow, W Duan, KSL Yeo… - International …, 2004 - Elsevier
Upon cross-linking of the high-affinity IgE receptors on mast cells, a family of mitogen-
activated protein kinases (MAPKs) is activated. The present study examined the effects of …
activated protein kinases (MAPKs) is activated. The present study examined the effects of …
Therapeutic modulation of signal transduction pathways
M Löwenberg, MP Peppelenbosch… - Inflammatory Bowel …, 2004 - academic.oup.com
Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder of the
gastrointestinal tract, which arises from inappropriate activation of the immune system. The …
gastrointestinal tract, which arises from inappropriate activation of the immune system. The …
[PDF][PDF] b2-Integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and b2-adrenoceptor activation in human eosinophils
J Liua, NM Munoza, AY Melitona, X Zhua… - Pulmonary …, 2004 - academia.edu
We investigated the effect and mechanism (s) of PDE-4 treatment with concurrent b2-
adrenoceptor stimulation on human eosinophil adhesion mediated by b2-integrin in vitro …
adrenoceptor stimulation on human eosinophil adhesion mediated by b2-integrin in vitro …