Cell adhesion, polarity, and epithelia in the dawn of metazoans

M Cereijido, RG Contreras… - Physiological …, 2004 - journals.physiology.org
Transporting epithelia posed formidable conundrums right from the moment that Du Bois
Raymond discovered their asymmetric behavior, a century and a half ago. It took a century …

Ouabain Binding to Na+,K+-ATPase Relaxes Cell Attachment and Sends a SpecificSignal (NACos) to the Nucleus

RG Contreras, C Flores-Maldonado, A Lazaro… - The Journal of …, 2004 - Springer
In previous work we described a “P→ A mechanism” that transduces occupancy of the pump
(P) by ouabain into changes in phosphorylation, stimulation of mitogen-activated protein …

Na+/K+ pump and endothelial cell survival:[Na+] i/[K+] i-independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na+] i

SN Orlov, N Thorin-Trescases, D Pchejetski, S Taurin… - Pflügers Archiv, 2004 - Springer
Recent studies have demonstrated the tissue-specific effect of Na+/K+ pump inhibition by
ouabain and other cardiac glycosides on cell viability. The vascular endothelium is an initial …

Antiapoptotic effect of ouabain on human umbilical vein endothelial cells

L Trevisi, B Visentin, F Cusinato, I Pighin… - … and biophysical research …, 2004 - Elsevier
The present study investigates the effect of ouabain on caspase-3 activation in human
umbilical vein endothelial cells (HUVEC). Ouabain (EC50 20nM) reduced caspase-3 activity …

Functional Innervation in Tissue Engineered Models for In Vitro Study and Testing Purposes

EJ Suuronen, CR McLaughlin, PK Stys… - Toxicological …, 2004 - academic.oup.com
The biotechnology industry is rapidly expanding and the emerging field of tissue
engineering is projected to have a high impact in the near future. Recently the field of …

Apoptosis VS. Oncosis: Role of Cell Volume and Intracellular Monovalent Cations

SN Orlov, P Hamet - Cell Volume and Signaling, 2004 - Springer
Several research teams have proposed that shrinkage and swelling in cells undergoing
apoptosis and oncosis are not only the earliest morphological markers of the two modes of …

Angiotensin as a cytokine implicated in accelerated cellular turnover

P Hamet, SN Orlov, D DeBlois, Y Sun, V Kren… - Angiotensin Vol. I, 2004 - Springer
Several models of essential hypertension have revealed abnormalities in pathways
regulating cell proliferation and programmed cell death (apoptosis). The increased …

[PDF][PDF] Na/K pump and endothelial cell survival:[Na] i/[K] i-independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na] i

SNON Thorin-Trescases, DPSTN Farhat… - Pflugers Arch-Eur J …, 2004 - academia.edu
Recent studies have demonstrated the tissuespecific effect of Na+/K+ pump inhibition by
ouabain and other cardiac glycosides on cell viability. The vascular endothelium is an initial …

[引用][C] Na^+-K^+-ATP 酶抑制引起的细胞凋亡和杂合性细胞死亡

徐瑞成, 张敏 - 细胞生物学杂志, 2004