Purpose Many children diagnosed with retinoblastoma (Rb) survive into adulthood and are
prone to subsequent cancers, particularly hereditary patients, who have germline Rb-1 …

The past 3 decades have seen tremendous improvements in the survival of children
diagnosed with cancer, with the 15-year survival rate approaching 80%. This improvement …

Purpose: Radiation-induced osteosarcomas (R-OS) have historically been high-grade,
locally invasive tumors with a poor prognosis. The purpose of this study was to perform a …

Background. To quantify the risk of soft tissue and bone sarcomas after breast cancer
according to the doses and technical modalities of irradiation. Methods. We followed a …

BACKGROUND Previous studies have shown that children who are treated for soft tissue
sarcoma (STS) are at increased risk for developing second cancers. However, the risk for …

To evaluate the incidence, risk factors and prognosis for solid tumors after hematopoietic
stem cell transplantation (HSCT) in Japan, 809 patients who had received HSCT between …

Study Design. A retrospective analysis was performed. Objectives. To determine the
oncological outcome of patients with nonmetastatic Ewing's sarcoma of the mobile spine …

Ewing's sarcoma is the second most common primary bone tumor seen in children and
adolescents, and was described by James Ewing in 1921 as a diffuse endothelioma of …

Although treatment of pediatric Hodgkin disease has become highly effective over the past
40 years, a number of patients have developed concerning late effects, such as secondary …

The relative risk of second tumors in patients with Ewing sarcoma is controversial, and little
is known about their treatment and outcome. The purpose of the current study was to define …