The regulated ability of integrin αIIbβ3 to bind fibrinogen plays a crucial role in platelet
aggregation and hemostasis. We have developed a model system based on laser tweezers …

Хроническая сердечная недостаточность (ХСН) является одной из актуальных
проблем здравоохранения в развитых странах мира, учитывая ее распространенность …

The term integrin describes an adhesion molecule family and originates from the integrative
function of these molecules between extracellular ligands and the intracellular cytoskeleton …

Platelets are involved in the development of arteriosclerosis as well as in acute thrombotic
events. Physical exercise helps to avoid arteriosclerosis, but acute intensive exercise seems …

Although Bizzozero identified platelets as a blood component critical for hemostasis in 1882
(1), the central role of platelets in atherogenesis is just now being recognized (2). During …