Uric acid is the final product of purine metabolism in humans. The final two reactions of its
production catalyzing the conversion of hypoxanthine to xanthine and the latter to uric acid …

According to the free radical theory, aging can be considered as a progressive, inevitable
process partially related to the accumulation of oxidative damage into biomolecules–nucleic …

Twenty-four dairy cows were monitored during the transition period. We observed changes
of oxidative status and relationships between oxidative and metabolic status. Body condition …

Nutritional, or dietary oxidative stress denotes a disturbance of the redox state resulting from
excess oxidative load or from inadequate nutrient supply favoring prooxidant reactions. Low …

Free radical production is increased in ischemic and hemorrhagic stroke, leading to
oxidative stress that contributes to brain damage. The measurement of oxidative stress in …

Metabolic processes which generate oxidants and antioxidants are governed by genetic
disposition as well as environmental factors. Changes in lifestyle, including increased …

Deoxyribonucleic acid (DNA) appears to be a critical cellular target for the biological effects
(cellular lethality, mutagenesis, carcinogenesis, and ageing) of oxidation processes …

Venous leg ulcers are common and cause considerable morbidity in the population. As
healing may be slow or may never be achieved, ulcers create persistent and substantial …

Tumor necrosis factor (TNF) is a proinflammatory cytokine that plays a critical role in diverse
cellular events, including cell proliferation, differentiation and apoptosis. TNF is also …

For a decade or two, the hypothesis of causality of various disorders by reactive oxygen
species (ROS), due to their potentially harmful effect towards cellular constituents, is one of …