Amyloid‐related diseases are often ascribed to protein “misfolding.” Yet in the absence of
high‐resolution structures for mature fibrils or intermediates, the connection between the …

Recent studies have begun to investigate the role of agrin in brain and suggest that agrin's
function likely extends beyond that of a synaptogenic protein. Particularly, it has been shown …

Biochemical characterization of the major detergent‐insoluble proteins that comprise
hallmark histopathologic lesions initiated the molecular era of Alzheimer's disease (AD) …

There is a growing consensus that microvascular damage is an important contributing factor
to the pathogenesis of dementia (1). Increased vascular tortuosity and narrowing is a …

The main neurodegenerative diseases can be loosely grouped into two broad categories—
memory disorders or 'dementias' such as Alzheimer's disease (AD) and movement disorders …