[HTML][HTML] Identification of multiple HLA-A* 0201-restricted cruzipain and FL-160 CD8+ epitopes recognized by T cells from chronically Trypanosoma cruzi-infected …

SG Fonseca, H Moins-Teisserenc, E Clave, B Ianni… - Microbes and …, 2005 - Elsevier
Chronic Chagas disease occurs in 16 million individuals chronically infected by the
protozoan Trypanosoma cruzi in Latin America, and may lead to a dilated cardiomyopathy in …

Type 1 immunity provides both optimal mucosal and systemic protection against a mucosally invasive, intracellular pathogen

DF Hoft, CS Eickhoff - Infection and immunity, 2005 - Am Soc Microbiol
It has been hypothesized that optimal vaccine immunity against mucosally invasive,
intracellular pathogens may require the induction of different types of immune responses in …

Caspase-8 activity prevents type 2 cytokine responses and is required for protective T cell-mediated immunity against Trypanosoma cruzi infection

EM Silva, LVC Guillermo… - The Journal of …, 2005 - journals.aai.org
During Trypanosoma cruzi infection, T cells up-regulate caspase-8 activity. To assess the
role of caspase-8 in T cell-mediated immunity, we investigated the effects of caspase-8 …

Trypanosoma cruzi Posttranscriptionally Up-Regulates and Exploits Cellular FLIP for Inhibition of Death-inducing Signal

M Hashimoto, J Nakajima-Shimada… - Molecular biology of the …, 2005 - Am Soc Cell Biol
Intracellular persistence of the protozoan parasite, Trypanosoma cruzi, is an aggravating
cause of Chagas' disease, involving that the protozoan infection specifically inhibits death …

Humoral and cellular immune responses in BALB/c and C57BL/6 mice immunized with cytoplasmic (CRA) and flagellar (FRA) recombinant repetitive antigens, in …

VRA Pereira, VMB Lorena, M Nakazawa, CF Luna… - Parasitology …, 2005 - Springer
In previous studies, cytoplasmic repetitive antigen (CRA) and flagellar repetitive antigen
(FRA) proteins induced specific humoral and cellular immune responses in susceptible and …

[PDF][PDF] Caspase-8 Activity Prevents Type 2 Cytokine

MF Lopes, UG Lopes, RM Siegel, GA DosReis, Z Wu… - J Immunol, 2005 - academia.edu
During Trypanosoma cruzi infection, T cells up-regulate caspase-8 activity. To assess the
role of caspase-8 in T cell-mediated immunity, we investigated the effects of caspase-8 …

Migração de células inflamatórias para o tecido cardíaco durante a fase aguda precoce da infecção experimental pelo Trypanosoma cruzi: identificação de alvos …

APMP Marino - 2005 - pesquisa.bvsalud.org
ABSTRACT A compreensão da patogênese da miocardite induzida pelo Trypanosoma cruzi
é crucial para delinear estratégias que reduzam a inflamação, que leva a disfunção …