Understanding the emergence of new zoonotic agents requires knowledge of pathogen biodiversity in wildlife, human-wildlife interactions, anthropogenic pressures on wildlife …
S Hué, D Pillay, JP Clewley… - Proceedings of the …, 2005 - National Acad Sciences
We explored the epidemic history of HIV-1 subtype B in the United Kingdom by using statistical methods that infer the population history of pathogens from sampled gene …
Genetic diversity in pathogen species contains information about evolutionary and epidemiological processes, including the origins and history of disease, the nature of the …
PR Walker, OG Pybus, A Rambaut… - Infection, Genetics and …, 2005 - Elsevier
The human immunodeficiency virus (HIV) pandemic continues to grow at an alarming rate, with a further 5 million new infections in 2003. Some 3.5 million of these were in sub …
PM Coplan, SB Gupta, SA Dubey… - The Journal of …, 2005 - academic.oup.com
Background The genetic diversity of human immunodeficiency virus type 1 (HIV-1) raises the question of whether vaccines that include a component to elicit antiviral T cell immunity …
HIV, the cause of AIDS in humans, is characterized by great genetic heterogeneity. In particular, HIV-1 group M subtypes are responsible for most of the infections worldwide. We …
M Altfeld, TM Allen, ET Kalife, N Frahm… - Journal of …, 2005 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) mutates to escape immune selection pressure, but there is little evidence of selection mediated through HLA-A2, the dominant …
G Bello, C Casado, V Sandonis… - Journal of general …, 2005 - microbiologyresearch.org
Within human immunodeficiency virus type 1 (HIV-1)-infected patients, there are those who have been infected for more than 10 years with a CD4+ cell count of> 500 cells μl− 1 and …
S Pantano, P Carloni - Proteins: Structure, Function, and …, 2005 - Wiley Online Library
HIV‐1 Tat protein is a crucial element for viral replication; therefore, its inhibition might be exploited against the AIDS infection. To gain insights on the natural variability of this protein …