The neurodevelopmental model of schizophrenia: update 2005

JL Rapoport, AM Addington, S Frangou… - Molecular …, 2005 - nature.com
Neurodevelopmental models of schizophrenia that identify longitudinal precursors of illness
have been of great heuristic importance focusing most etiologic research over the past two …

Environmental risk factors for psychosis

K Dean, RM Murray - Dialogues in clinical neuroscience, 2005 - Taylor & Francis
Genetic factors are clearly important in the etiology of schizophrenia, but the environment in
which an individual's genes find expression is also crucial to the development of the illness …

Bipolar I disorder and schizophrenia: a 440–single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios

MD Fallin, VK Lasseter, D Avramopoulos… - The American Journal of …, 2005 - cell.com
Bipolar, schizophrenia, and schizoaffective disorders are common, highly heritable
psychiatric disorders, for which familial coaggregation, as well as epidemiological and …

Predictors of schizophrenia—a review

P Mäki, J Veijola, PB Jones, GK Murray… - British medical …, 2005 - academic.oup.com
Schizophrenia is an aetiologically heterogeneous syndrome that usually becomes overtly
manifest in adolescence and early adulthood, but in many cases subtle impairments in …

A psychological model of mental disorder

P Kinderman - Harvard review of psychiatry, 2005 - journals.lww.com
A coherent conceptualization of the role of psychological factors is of great importance in
understanding mental disorder. Academic articles and professional reports alluding to …

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression

NJ Bray, A Preece, NM Williams… - Human molecular …, 2005 - academic.oup.com
The DTNBP1 gene, encoding dysbindin, is now generally considered to be a susceptibility
gene for schizophrenia. However, the confidence with which this hypothesis can be held has …

Morbid risk for psychiatric disorder among the relatives of methamphetamine users with and without psychosis

CK Chen, SK Lin, PC Sham, D Ball… - American Journal of …, 2005 - Wiley Online Library
It is not clear why some methamphetamine (MAMP) abusers develop psychotic symptoms,
while others use MAMP regularly over long periods and remain unscathed. We tested the …

Shared and specific susceptibility loci for schizophrenia and bipolar disorder: a dense genome scan in Eastern Quebec families

M Maziade, MA Roy, YC Chagnon, D Cliche… - Molecular …, 2005 - nature.com
The goal of this study was to identify susceptibility loci shared by schizophrenia (SZ) and
bipolar disorder (BP), or specific to each. To this end, we performed a dense genome scan …

Memory and verbal learning functions in twins with bipolar-I disorder, and the role of information-processing speed

T Kieseppä, A Tuulio-Henriksson, J Haukka… - Psychological …, 2005 - cambridge.org
Background. Euthymic bipolar-I disorder (BP I) patients and their siblings have shown
impairments in verbal learning and memory functions compared with controls, suggesting …

Risk for schizophrenia—broadening the concepts, pushing back the boundaries

M Cannon, MC Clarke - Schizophrenia research, 2005 - Elsevier
This paper gives an overview of environmental risk factors for schizophrenia. The presence
of certain biological and psychosocial factors at certain points in the lifespan has been …