Ru360, a specific mitochondrial calcium uptake inhibitor, improves cardiac post‐ischaemic functional recovery in rats in vivo

G de J García‐Rivas, K Carvajal… - British journal of …, 2006 - Wiley Online Library
Background and purpose: The mitochondrial permeability transition pore (mPTP), an energy‐
dissipating channel activated by calcium, contributes to reperfusion damage by depolarizing …

Cardiac mast cell–derived renin promotes local angiotensin formation, norepinephrine release, and arrhythmias in ischemia/reperfusion

CJ Mackins, S Kano, N Seyedi… - The Journal of …, 2006 - Am Soc Clin Investig
Having identified renin in cardiac mast cells, we assessed whether its release leads to
cardiac dysfunction. In Langendorff-perfused guinea pig hearts, mast cell degranulation with …

Effects of sleep deprivation on cardiac autonomic and pituitary-adrenocortical stress reactivity in rats

A Sgoifo, B Buwalda, M Roos, T Costoli… - …, 2006 - Elsevier
A demanding life style, often associated with restricted time for sleep, is a growing problem
in our society and may become a major health issue in the near future. Since the …

Autologous myoblast transplantation after myocardial infarction increases the inducibility of ventricular arrhythmias

S Fernandes, JC Amirault, G Lande… - Cardiovascular …, 2006 - academic.oup.com
Background: Small scale clinical trials suggested the feasibility and the efficacy of
autologous myoblast transplantation to improve ventricular function after myocardial …

Resveratrol, a natural ingredient of grape skin: antiarrhythmic efficacy and ionic mechanisms

Y Zhang, Y Liu, T Wang, B Li, H Li, Z Wang… - … and biophysical research …, 2006 - Elsevier
Resveratrol has been demonstrated to produce a variety of biological actions. Accumulating
line of evidence supported the view that resveratrol may exert protective effect on the …

Rotigaptide (ZP123) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs

JK Hennan, RE Swillo, GA Morgan, JC Keith… - … of Pharmacology and …, 2006 - ASPET
The antiarrhythmic and cardioprotective effect of increasing gap junction intercellular
communication during ischemia/reperfusion injury has not been studied. The antiarrhythmic …

NADPH oxidases are in part responsible for increased cardiovascular superoxide production during aging

A Oudot, C Martin, D Busseuil, C Vergely… - Free Radical Biology …, 2006 - Elsevier
The aim of our study was to examine in rats, age-related differences in myocardial ischemic
recovery and to determine the possible relationship with modification of cardiac and …

Greater antiarrhythmic activity of acute 17β‐estradiol in female than male anaesthetized rats: correlation with Ca2+ channel blockade

KL Philp, M Hussain, NF Byrne, MJ Diver… - British journal of …, 2006 - Wiley Online Library
Background and purpose: Female sex hormones may protect pre‐menopausal women from
sudden cardiac death. We therefore investigated the effects of the main female sex …

β1-Adrenergic receptor antagonism abrogates cardioprotective effects of intermittent hypoxia

RT Mallet, MG Ryou, AG Williams, L Howard… - Basic research in …, 2006 - Springer
Adaptation to hypoxia lessens myocardial ischemic injury. This study tested whether hypoxia-
induced β-adrenergic activity mobilizes mechanisms that protect myocardium during …

Similarities between ischemic preconditioning and 17β-estradiol mediated cardiomyocyte KATP channel activation leading to cardioprotective and antiarrhythmic …

B Das, C Sarkar - Journal of cardiovascular pharmacology, 2006 - journals.lww.com
The aims of our present work were to assess whether treatment with either ischemic
preconditioning (IPC) or 17β-estradiol or both combined produce proarrhythmic or …