[PDF][PDF] Machine learning in bioinformatics

P Larranaga, B Calvo, R Santana… - Briefings in …, 2006 - academic.oup.com
This article reviews machine learning methods for bioinformatics. It presents modelling
methods, such as supervised classification, clustering and probabilistic graphical models for …

[9] TM4 microarray software suite

AI Saeed, NK Bhagabati, JC Braisted, W Liang… - Methods in …, 2006 - Elsevier
Powerful specialized software is essential for managing, quantifying, and ultimately deriving
scientific insight from results of a microarray experiment. We have developed a suite of …

Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues

Y Murakami, T Yasuda, K Saigo, T Urashima, H Toyoda… - Oncogene, 2006 - nature.com
MicroRNAs (miRNAs) are a non-coding family of genes involved in post-transcriptional gene
regulation. These transcripts are associated with cell proliferation, cell differentiation, cell …

A geometric approach to support vector machine (SVM) classification

ME Mavroforakis, S Theodoridis - IEEE transactions on neural …, 2006 - ieeexplore.ieee.org
The geometric framework for the support vector machine (SVM) classification problem
provides an intuitive ground for the understanding and the application of geometric …

Automated protein function prediction—the genomic challenge

I Friedberg - Briefings in bioinformatics, 2006 - academic.oup.com
Overwhelmed with genomic data, biologists are facing the first big post-genomic question—
what do all genes do? First, not only is the volume of pure sequence and structure data …

Discovery and validation of new protein biomarkers for urothelial cancer: a prospective analysis

D Theodorescu, S Wittke, MM Ross, M Walden… - The lancet …, 2006 - thelancet.com
Background Non-invasive methods for diagnosis of urothelial carcinoma have reduced
specificity in patients with non-malignant genitourinary disease or other disorders. We aimed …

Machine learning techniques in disease forecasting: a case study on rice blast prediction

R Kaundal, AS Kapoor, GPS Raghava - BMC bioinformatics, 2006 - Springer
Background Diverse modeling approaches viz. neural networks and multiple regression
have been followed to date for disease prediction in plant populations. However, due to their …

Prediction of sensitivity of rectal cancer cells in response to preoperative radiotherapy by DNA microarray analysis of gene expression profiles

T Watanabe, Y Komuro, T Kiyomatsu, T Kanazawa… - Cancer research, 2006 - AACR
Preoperative radiotherapy has been widely used to improve local control of disease and to
improve survival in the treatment of rectal cancer. However, the response to radiotherapy …

CARMAweb: comprehensive R-and bioconductor-based web service for microarray data analysis

J Rainer, F Sanchez-Cabo, G Stocker… - Nucleic acids …, 2006 - academic.oup.com
Abstract CARMAweb (Comprehensive R-based Microarray Analysis web service) is a web
application designed for the analysis of microarray data. CARMAweb performs data …

Classification using functional data analysis for temporal gene expression data

X Leng, HG Müller - Bioinformatics, 2006 - academic.oup.com
Motivation: Temporal gene expression profiles provide an important characterization of gene
function, as biological systems are predominantly developmental and dynamic. We propose …