The major histocompatibility complex, sexual selection, and mate choice

M Milinski - Annu. Rev. Ecol. Evol. Syst., 2006 - annualreviews.org
To maintain sexual reproduction, recombination of good genes through selective mate
choice must achieve a twofold genetic benefit in each generation.“Fragrant” immune genes …

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene

RP Nair, PE Stuart, I Nistor, R Hiremagalore… - The American Journal of …, 2006 - cell.com
Previous studies have narrowed the interval containing PSORS1, the psoriasis-susceptibility
locus in the major histocompatibility complex (MHC), to an∼ 300-kb region containing HLA …

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC

PIW De Bakker, G McVean, PC Sabeti, MM Miretti… - Nature …, 2006 - nature.com
The proteins encoded by the classical HLA class I and class II genes in the major
histocompatibility complex (MHC) are highly polymorphic and are essential in self versus …

Tissue-specific differences in human transfer RNA expression

KA Dittmar, JM Goodenbour, T Pan - PLoS genetics, 2006 - journals.plos.org
Over 450 transfer RNA (tRNA) genes have been annotated in the human genome. Reliable
quantitation of tRNA levels in human samples using microarray methods presents a …

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions

SI Hung, WH Chung, SH Jee, WC Chen… - Pharmacogenetics …, 2006 - journals.lww.com
The anticonvulsant carbamazepine (CBZ) frequently causes cutaneous adverse drug
reactions (cADRs), including maculopapular eruption (MPE), hypersensitivity syndrome …

DNA analysis by mass spectrometry—past, present and future

J Tost, IG Gut - Journal of mass spectrometry, 2006 - Wiley Online Library
The analysis of deoxyribose nucleic acid (DNA) by mass spectrometry (MS) has evolved to
where it can be used to analyze most known types of DNA and ribose nucleic acid (RNA) …

[HTML][HTML] The genomic sequence and analysis of the swine major histocompatibility complex

C Renard, E Hart, H Sehra, H Beasley, P Coggill… - Genomics, 2006 - Elsevier
We describe the generation and analysis of an integrated sequence map of a 2.4-Mb region
of pig chromosome 7, comprising the classical class I region, the extended and classical …

Ancestral organization of the MHC revealed in the amphibian Xenopus

Y Ohta, W Goetz, MZ Hossain, M Nonaka… - The Journal of …, 2006 - journals.aai.org
With the advent of the Xenopus tropicalis genome project, we analyzed scaffolds containing
MHC genes. On eight scaffolds encompassing 3.65 Mbp, 122 MHC genes were found of …

[HTML][HTML] Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation

T Aoto, N Saitoh, T Ichimura, H Niwa, M Nakao - Developmental biology, 2006 - Elsevier
Epigenetic gene control is involved in mechanisms of development. Little is known about the
cooperation of nuclear and chromatin events in programmed differentiation from mouse …

Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products

SB Qian, E Reits, J Neefjes, JM Deslich… - The Journal of …, 2006 - journals.aai.org
There is mounting evidence that MHC class I peptide ligands are predominantly generated
from defective ribosomal products and other classes of polypeptides degraded rapidly (t …