Over 40 nonhuman primate (NHP) species harbor species-specific simian
immunodeficiency viruses (SIVs). Similarly, more than 20 species of nondomestic felids and …

The human immunodeficiency virus (HIV) type-1 viral protein U (Vpu) protein enhances the
release of diverse retroviruses from human, but not monkey, cells and is thought to do so by …

The HIV‐1 accessory gene product Vpu is required for efficient viral particle release from
infected human cells. The mechanism by which Vpu enhances particle assembly or release …

Cross-species transmission of retroviruses poses a threat to mammalian species. Zoonoses
have given rise to devastating diseases because the host organism is not prepared to resist …

Recent studies indicate that human immunodeficiency virus type 1 (HIV-1) recombines at
exceedingly high rates, approximately 1 order of magnitude more frequently than simple …

Although it is now well established that a substantial proportion of wild-living primates in sub-
Saharan Africa harbor SIV, no study to date has examined to what extent the various species …

The Vpu protein of human immunodeficiency virus type 1 has been shown to shunt the CD4
receptor molecule to the proteasome for degradation and to enhance virus release from …

Based on structures made available by solution NMR, molecular models of the protein Vpu
from HIV-1 were built and refined by 6 ns MD simulations in a fully hydrated lipid bilayer …

选取了16 株SIV 和9 株HIV 毒株, 以人T 细胞白血病病毒HTLV-1 为outgroup, 使用CLUSTAL X,
PHYLIP 及MEGA 三种软件对它们的基因组序列及三个主要蛋白(Env, Gag, Pol) …

La sous-unité transmembranaire, gp4l, de la glycoprotéine virale du VIH 1, se subdivise en
trois domaines qui ont chacun des rôles distincts. De nombreuses études ont démontré …