Selective neuronal degeneration in Huntington's disease
CM Cowan, LA Raymond - Current topics in developmental biology, 2006 - Elsevier
Huntington's disease (HD) is a progressive neurodegenerative disorder that generally
begins in middle age with abnormalities of movement, cognition, personality, and mood …
begins in middle age with abnormalities of movement, cognition, personality, and mood …
Striatal specificity of gene expression dysregulation in Huntington's disease
EA Thomas - Journal of neuroscience research, 2006 - Wiley Online Library
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by an
expanded CAG repeat region in exon 1 of the HD gene. This mutation results in the …
expanded CAG repeat region in exon 1 of the HD gene. This mutation results in the …
Methamphetamine-induced cell death: selective vulnerability in neuronal subpopulations of the striatum in mice
JPQ Zhu, W Xu, JA Angulo - Neuroscience, 2006 - Elsevier
Methamphetamine (METH) is an illicit and potent psychostimulant, which acts as an indirect
dopamine agonist. In the striatum, METH has been shown to cause long lasting neurotoxic …
dopamine agonist. In the striatum, METH has been shown to cause long lasting neurotoxic …
Cellular and molecular mechanisms involved in the selective vulnerability of striatal projection neurons in Huntingtons disease
E Perez-Navarro, JM Canals, S Gines… - Histology and …, 2006 - digitum.um.es
Neurodegenerative disorders affecting the central nervous system, such as Alzheimer's
disease, Parkinson's disease, Huntington's chorea (HD) and amyotrophic lateral sclerosis …
disease, Parkinson's disease, Huntington's chorea (HD) and amyotrophic lateral sclerosis …
In vivo characterization of caspase resistant huntingtin: insights into the pathogenic mechanism of Huntington disease
RK Graham - 2006 - open.library.ubc.ca
Proteolytic cleavage of htt is regarded as a critical event in the pathogenesis of HD.
Expression of htt fragments containing an expanded polyglutamine repeat are toxic in vitro …
Expression of htt fragments containing an expanded polyglutamine repeat are toxic in vitro …
[图书][B] Methamphetamine-induced cell death in the striatum and the role of neurokinin-1 receptor in its pathogeny
JPQ Zhu - 2006 - search.proquest.com
Methamphetamine (METH) is a potent psychostimulant known to cause extensive neural
damage in the central nervous system. Continued characterization of its neural effects …
damage in the central nervous system. Continued characterization of its neural effects …
[引用][C] Animal Models of Huntington's Disease
IJ Mitchell - Animal Models Of Neuropsychiatric Diseases, 2006 - World Scientific
The following sections are included: Summary Introduction Major Characteristics of
Huntington's Disease—Genetics Major Characteristics of Huntington's Disease—Symptoms …
Huntington's Disease—Genetics Major Characteristics of Huntington's Disease—Symptoms …