Oxidative stress is often defined as an imbalance of pro-oxidants and antioxidants, which
can be quantified in humans as the redox state of plasma GSH/GSSG. Plasma GSH redox in …

Reactive oxygen species (ROS) have been shown to function as important signaling
molecules in the cardiovascular system. Vascular smooth muscle cells (VSMCs) contain …

Altered antioxidant status has been reported in schizophrenia. The glutathione (GSH) redox
system is important for reducing oxidative stress. GSH, a radical scavenger, is converted to …

Reactive oxygen species (ROS) have captured the interest of many researchers in the
chemical, biological, and medical fields since they are thought to be associated with various …

NF-κB is an inducible transcription factor that plays a role in the expression of over one
hundred genes involved in immunity, inflammation, proliferation, and in defense against …

Metal toxicity often includes the generation of reactive oxygen species (ROS) and
subsequent oxidative stress, but whether metals have different effects on the major thiol …

Modulation of signaling in vascular cells by reactive oxygen species (ROS) affects many
aspects of cellular function, including growth, migration, and contraction. NADPH oxidases …

Protein thiol oxidation subserves important biological functions and constitutes a sequel of
reactive oxygen species toxicity. We developed two distinct thiol-labeling approaches to …

The present review and commentary considers oxidative stress as a disruption of
mitochondrial redox circuitry rather than an imbalance of oxidants and antioxidants …

The biological and toxicological effects that have been attributed to reactive nitrogen species
(RNS) are increasingly stirring the scientific inquisitiveness about the molecular …