Extracellular signal-regulated kinase as an inducer of non-apoptotic neuronal death

S Subramaniam, K Unsicker - Neuroscience, 2006 - Elsevier
Extracellular signal-regulated kinase (ERK) is a versatile protein kinase, which has been
implicated in signaling numerous biological functions ranging from embryonic development …

Ca2+ influx through CRAC channels activates cytosolic phospholipase A2, leukotriene C4 secretion, and expression of c‐fos through ERK‐dependent and …

WC Chang, C Nelson, AB Parekh… - The FASEB …, 2006 - Wiley Online Library
Cytosolic phospholipase A2 (cPLA2) is a Ca2+‐dependent enzyme that mediates agonist‐
dependent arachidonic acid release in most cell types. Arachidonic acid can then be …

Mechanotransduction of stretch-induced prostanoid release by fetal lung epithelial cells

IB Copland, D Reynaud… - American Journal of …, 2006 - journals.physiology.org
Mechanical ventilation is the primary supportive treatment for infants and adults suffering
from severe respiratory failure. Adverse mechanical ventilation (overdistension of the lung) …

Differential production of leukotriene B4 or prostaglandin E2 by WKYMVm or serum amyloid A via formyl peptide receptor-like 1

HY Lee, SH Jo, C Lee, SH Baek, YS Bae - Biochemical pharmacology, 2006 - Elsevier
Serum amyloid A (SAA) and Trp-Lys-Tyr-Met-Val-D-Met (WKYMVm) have been reported as
formyl peptide receptor-like 1 (FPRL1) ligands. WKYMVm but not SAA stimulated …

IL-1β signaling in cat lower esophageal sphincter circular muscle

W Cao, L Cheng, J Behar… - American Journal of …, 2006 - journals.physiology.org
In a cat model of acute experimental esophagitis, resting in vivo lower esophageal sphincter
(LES) pressure and in vitro tone are lower than in normal LES, and the LES circular smooth …

Biphasic regulation of extracellular signal-regulated kinases by scalaradial, a secretory phospholipase A2 inhibitor

Y Xie, Z Yu, L Liu, Y Guo, L Lou - Cancer biology & therapy, 2006 - Taylor & Francis
The marine natural product scalaradial (SLD) is a potent inhibitor of secretory
phospholipase A2 (sPLA2). Our previous work has demonstrated that SLD inhibits …