Detecting and characterizing reactive metabolites by liquid chromatography/tandem mass spectrometry
S Ma, R Subramanian - Journal of mass spectrometry, 2006 - Wiley Online Library
Metabolic activation of a drug leading to reactive metabolite (s) that can covalently modify
proteins is considered an initial step that may lead to drug‐induced organ toxicities …
proteins is considered an initial step that may lead to drug‐induced organ toxicities …