It is generally accepted that electrochemical gradients of monovalent ions across the plasma
membrane, created by the coupled function of pumps, carriers and channels, are involved in …

Cardiotonic glycosides, like ouabain, inhibit Na+-K+-ATPase. Recent evidence suggests
that low molar concentrations of ouabain alter cell growth. Studies were conducted to …

Cell adhesion is a crucial step in proliferation, differentiation, migration, apoptosis, and
metastasis. In previous works we have shown that cell adhesion is modulated by ouabain, a …

The mgtC gene of Salmonella enterica serovar Typhimurium encodes a membrane protein
of unknown function that is important for full virulence in the mouse. Since mgtC is part of an …

Na/K‐ATPase is the only known target of cardiotonic steroids (CTS) identified in plants,
amphibians and later on in several mammalian species, including human. We focus our …

Decreased staining with dimethylthiazol diphenyltetrazolium (MTT) is widely used for cell
death detection. This study examined MTT assay as a marker of the Na+ i, K+ i-independent …

The signaling cascade resulting in the death of several types of cells treated with ouabain or
other cardiotonic steroids (CTS) remains poorly understood. Recently, we observed that …

Current evidence demonstrates that augmented production of endogenous cardiotonic
steroids (CTS) such as ouabain and marinobufagenin is involved in the pathogenesis of …