[HTML][HTML] Extracellular heat shock proteins in cell signaling

SK Calderwood, SS Mambula, PJ Gray Jr, JR Theriault - FEBS letters, 2007 - Elsevier
Extracellular stress proteins including heat shock proteins (Hsp) and glucose regulated
proteins (Grp) are emerging as important mediators of intercellular signaling and transport …

HIV entry inhibitors

JA Esté, A Telenti - The Lancet, 2007 - thelancet.com
The need for new classes of antiretroviral drugs has become apparent because of
increasing concern about the long-term toxic effects of existing drugs, the need to combat …

Host Innate Immune Response to Mycobacterium tuberculosis

K Bhatt, P Salgame - Journal of clinical immunology, 2007 - Springer
This review focuses on recent progress in our understanding of Mycobacterium tuberculosis
survival in macrophages, the interaction of M. tuberculosis with Toll-like receptors (TLRs) …

Extracellular heat shock proteins in cell signaling and immunity

SK Calderwood, SS Mambula… - Annals of the New York …, 2007 - Wiley Online Library
Extracellular stress proteins including heat shock proteins (Hsps) and glucose‐regulated
proteins (Grps) are emerging as important mediators of intercellular signaling and transport …

Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of …

RA Floto, S Sarkar, EO Perlstein, B Kampmann… - Autophagy, 2007 - Taylor & Francis
Upregulation of autophagy may have therapeutic benefit in a range of diseases that include
neurodegenerative conditions caused by intracytosolic aggregate-prone proteins, such as …

Structure and function: heat shock proteins and adaptive immunity

B Javid, PA MacAry, PJ Lehner - The Journal of Immunology, 2007 - journals.aai.org
Heat shock proteins (HSPs) have been implicated in the stimulation and generation of both
innate and adaptive immunity. The ability of HSPs to bind antigenic peptides and deliver …

Cell surface receptors for molecular chaperones

SK Calderwood, J Theriault, PJ Gray, J Gong - Methods, 2007 - Elsevier
Heat shock proteins are intracellular molecular chaperones. However, extracellular heat
shock proteins have recently been shown to mediate a range of powerful effects in …

[HTML][HTML] Interactions of pathogenic mycobacteria with host macrophages

V Sundaramurthy, J Pieters - Microbes and Infection, 2007 - Elsevier
Tuberculosis, caused by the bacterium Mycobacterium tuberculosis, is one of the most
deadly infectious diseases across the globe. The success of M. tuberculosis is related to its …

Access denied? The status of co-receptor inhibition to counter HIV entry

P Biswas, G Tambussi, A Lazzarin - Expert opinion on …, 2007 - Taylor & Francis
As resistance and long-term metabolic abnormalities hamper the efficacy of previous drugs
against HIV-1, targeting of HIV co-receptors represents an exciting new frontier for …

[HTML][HTML] Flagellin contamination of recombinant heat shock protein 70 is responsible for its activity on T cells

Z Ye, YH Gan - Journal of Biological Chemistry, 2007 - ASBMB
Heat shock proteins (Hsp) 60 and 70 have been intensively studied for their ability to
activate innate immunity. Heat shock proteins had been shown to induce the activation of …