Aging is commonly defined as the accumulation of diverse deleterious changes occurring in
cells and tissues with advancing age that are responsible for the increased risk of disease …

Widespread aging at the population level is a recent phenomenon that emerged in affluent
societies. Inflammation is necessary to cope with damaging agents and is crucial for …

A progressive, systemic, and low-grade proinflammatory status is one of the major
characteristics of immunosenescence. Emerging data suggest a possible contribution of …

Osteoporosis is a common and severe condition in elderly men, which is poorly
characterized. In order to identify the hallmarks of age-related bone loss in the male …

The composite index constructed from longitudinal survey data as the level of deficits
accumulated by an individual (frailty index) captures important systemic aspects of …

Engajamento em atividades cognitivas e físicas está associado com a manutenção da
saúde cognitiva e com a prevenção de declínio cognitivo na população idosa. O objetivo do …

The relationships among lipoprotein metabolism, genetic vascular factors, vascular disease,
and Alzheimer's disease suggest that the examination of centenarian populations in relation …

Association analyses between gene variability and human longevity carried out by
comparing gene frequencies between population samples of different ages (case/control …

There has been no systematic study of the immune response of individuals aged over 60
years living in Schistosomiasis mansoni-endemic areas, although senescence is reportedly …

We report the influence of aging on multiple markers of oxidative-nitrosative stress in the
heart of adult (6-month), aged (30-month) and very aged (36-month) Fischer 344/NNiaHSd× …