OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice

J Zaini, S Andarini, M Tahara, Y Saijo… - The Journal of …, 2007 - Am Soc Clin Investig
The exceptional immunostimulatory capacity of DCs makes them potential targets for
investigation of cancer immunotherapeutics. We show here in mice that TNF-α–stimulated …

[HTML][HTML] Potential role of NKT regulatory cell ligands for the treatment of immune mediated colitis

M El Haj, AB Ya'acov, G Lalazar… - World Journal of …, 2007 - ncbi.nlm.nih.gov
Natural killer T lymphocytes (NKT) have been implicated in the regulation of autoimmune
processes in both mice and humans. In response to stimuli, this subset of cells rapidly …

Potential therapeutic role of natural killer cells in cancer

K Woan, V Reddy - Expert opinion on biological therapy, 2007 - Taylor & Francis
Cancer immunotherapy is a growing field that aims at restoring and enhancing immune
function to combat oncogenic conditions. One target of this field is natural killer (NK) cells …

Requirement for IFN-γ, CD8+ T Lymphocytes, and NKT Cells in Talactoferrin-Induced Inhibition of neu+ Tumors

M Spadaro, C Curcio, A Varadhachary, F Cavallo… - Cancer research, 2007 - AACR
We have previously shown that talactoferrin-alfa (TLF), a recombinant human lactoferrin, is
an immunomodulatory protein that is active against implanted tumors, both as a single agent …

Targeting sphingosine 1 phosphate receptor type 1 receptors in acute kidney injury

MD Okusa, KR Lynch - Drug Discovery Today: Disease Mechanisms, 2007 - Elsevier
Sphingosine 1-phosphate analogs have a multitude of effects with the best characterized
one being mediated through sphingosine 1-phosphate type 1 receptors (S1P1 receptor) …

小鼠NKT 细胞体外扩增的初步研究

郭蓉姣, 黄秀艳, 梁兆端, 曾耀英 - 哈尔滨医科大学学报, 2007 - cqvip.com
目的探索小鼠脾脏NKT 细胞的分离, 纯化及体外培养扩增的方法. 方法分离小鼠脾细胞,
制成单细胞悬液, α-半乳糖神经鞘胺醇(α-galactosylceramide, α-Galcer) 和rhIL-2 …

Натуральные киллеры Т-клетки (НКТ), иммунофенотипическая и функциональная характеристика, активация, значение в практической медицине

НК Ахматова, ЕА Лебединская… - Российский …, 2007 - elibrary.ru
Натуральные киллеры Т-клетки (НКТ)-уникальный подтип Т-лимфоцитов, вовлеченный
в регуляцию иммунного ответа и ассоциированный с числом заболеваний, включая рак …

An Improved Synthesis of Ceramide for Constructing α‐Galactosyl Ceramide Analogs

CH Yeh, SD Pan, SW Chen, ZW Fu… - Journal of the …, 2007 - Wiley Online Library
In spite of numerous synthetic routes to ceramide analogs, relatively few reports of the direct
coupling of the unprotected phytosphingosine with the activated palmitic acid via amide …

[PDF][PDF] Influence de la réponse inflammatoire et d'un traitement anti-inflammatoire sur le développement des gliomes

H Galarneau - 2007 - collectionscanada.gc.ca
Résumé Le rôle des macrophages dans le développement des gliomes, des tumeurs
attaquant le système nerveux central, est controversé. Nous avons étudié le développement …

[图书][B] Genetics and functions of innate-like lymphocyte subsets

J Rolf - 2007 - gupea.ub.gu.se
The immune system contains three different branches: innate immunity, adaptive immunity
and innate-like lymphocytes that share properties both with the innate and adaptive immune …