Chromatin structure imposes significant obstacles on all aspects of transcription that are
mediated by RNA polymerase II. The dynamics of chromatin structure are tightly regulated …

An important development in understanding the influence of chromatin on gene regulation
has been the finding that DNA methylation and histone post-translational modifications lead …

Over the past 10 years, the study of histone acetyltransferases (HATs) has advanced
significantly, and a number of HATs have been isolated from various organisms. It emerged …

Covalent modifications of histones are central to the regulation of chromatin dynamics, and,
therefore, many biological processes involving chromatin, such as replication, repair …

Trimethylation of histone H3 on lysine 4 (H3K4me3) localizes near the 5′ region of genes
and is tightly associated with active loci. Several proteins, such as CHD1, BPTF, JMJD2A …

Histones undergo several different post-translational modifications that control a variety of
physiological processes. These covalent modifications show substantial cross-regulation …

Seed dormancy is defined as the failure of a viable seed to germinate under favorable
conditions. Besides playing an adaptive role in nature by optimizing germination to the most …

Post-translational histone modifications have important regulatory roles in chromatin
structure and function,,. One example of such modifications is histone ubiquitination, which …

Deciphering the epigenetic" code" remains a central issue in transcriptional regulation.
Here, we report the identification of a JAMM/MPN+ domain-containing histone H2A …

Protein ubiquitination is critical for numerous cellular functions, including DNA damage
response pathways [1, 2]. Histones are the most abundant monoubiquitin conjugates in …