The over-expression of p53 H179Y residue mutation causes the increase of cyclin A1 and Cdk4 expression in HELF cells

D Yang, Y Qi, Q Chen, Z Wang, X Jin, J Gao… - Molecular and cellular …, 2007 - Springer
Down-regulation of p53 expression has been found in a broad range of human cancers and
cell proliferation disorders, indicating that p53 plays a key role in cell cycle regulation and …

p53 基因对人胚肺成纤维细胞周期影响的研究

杨迪, 高杰, 齐以涛, 陈倩, 王智琴, 傅娟玲, 周宗灿… - 癌变. 畸变. 突变, 2007 - cqvip.com
背景与目的: 研究野生型和179 位残基突变型p53 基因在HELF 细胞周期调控中的作用. 探讨p53
基因的179 位残基突变对细胞生长的影响. 材料与方法: 用野生型p53 (pcDNA3-wtp53) 和179 …

Identification and validation of novel amplification target genes in human breast cancer

C Ruiz - 2007 - edoc.unibas.ch
Gene amplification is a major mechanism for overexpression of potential oncogenes in
cancer. Several amplifications have already been described in breast cancer. In order to find …

[引用][C] p53 Protein in Breast Cancer-Current State of Knowledge

J Piekarski - Polish Journal of Surgery, 2007 - psjd.icm.edu.pl