The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

K Bedard, KH Krause - Physiological reviews, 2007 - journals.physiology.org
For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …

The interactions of flavonoids within neuronal signalling pathways

JPE Spencer - Genes & Nutrition, 2007 - Springer
Emerging evidence suggests that dietary phytochemicals, in particular flavonoids, may exert
beneficial effects in the central nervous system by protecting neurons against stress-induced …

Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways

P Yao, A Nussler, L Liu, L Hao, F Song… - Journal of …, 2007 - Elsevier
BACKGROUND/AIMS: Flavonoids, including quercetin, have been reported to have potent
hepatoprotective effects, which may be associated with HO-1 induction. However, since the …

Single-walled carbon nanotubes: geno-and cytotoxic effects in lung fibroblast V79 cells

ER Kisin, AR Murray, MJ Keane, XC Shi… - Journal of Toxicology …, 2007 - Taylor & Francis
With the development of nanotechnology, there is a tremendous growth of the application of
nanomaterials, which increases the risk of human exposure to these nanomaterials through …

Derivation of clinically compliant MSCs from CD105+, CD24− differentiated human ESCs

Q Lian, E Lye, K Suan Yeo, E Khia Way Tan… - Stem …, 2007 - academic.oup.com
Adult tissue-derived mesenchymal stem cells (MSCs) have demonstrated therapeutic
efficacy in treating diseases or repairing damaged tissues through mechanisms thought to …

Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells

WO Sampaio, C Henrique de Castro, RAS Santos… - …, 2007 - Am Heart Assoc
Angiotensin (Ang)-(1-7), acting through the Mas receptor, opposes the actions of Ang II.
Molecular mechanisms for this are unclear. Here we sought to determine whether Ang-(1-7) …

The carbonate radical and related oxidants derived from bicarbonate buffer

DB Medinas, G Cerchiaro, DF Trindade… - IUBMB life, 2007 - Wiley Online Library
The unequivocal demonstration that the carbonate radical (CO3•‐) is produced from the
reaction between the ubiquitous carbon dioxide and peroxynitrite, renewed the interest in …

Radioprotection and radiosensitization by curcumin

GC Jagetia - The Molecular Targets and Therapeutic Uses of …, 2007 - Springer
RADIOPROTECTION AND RADIOSENSITIZATION BY CURCUMIN Page 1 RADIOPROTECTION
AND RADIOSENSITIZATION BY CURCUMIN Ganesh C. Jagetia Abstract: This chapter gives …

ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells

S Zhuang, Y Yan, RA Daubert, J Han… - American Journal …, 2007 - journals.physiology.org
Reactive oxygen species, including hydrogen peroxide (H2O2), are generated during
ischemia-reperfusion and are critically involved in acute renal failure. The present studies …

Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage

HG Kim, DH Yoon, WH Lee, SK Han, B Shrestha… - Journal of …, 2007 - Elsevier
The mushroom Phellinus linteus has been known to exhibit potent biological activity. In
contrast to the immuno-potentiating properties of Phellinus linteus, the anti-inflammatory …