Abstract Background The Framingham Heart Study (FHS), founded in 1948 to examine the
epidemiology of cardiovascular disease, is among the most comprehensively characterized …

The investigations of patterns of linkage disequilibrium for designing associationmapping
studies are fast becoming a method of interest for complex trait dissection and improvement …

A SNP upstream of the INSIG2 gene, rs7566605, was recently found to be associated with
obesity as measured by body mass index (BMI) by Herbert and colleagues. The association …

Purpose A previous study has reported evidence of a strong linkage, but no association,
between paired box gene 6 (PAX6) and myopia. We attempted to replicate these findings …

Murine models and association studies in eating disorder (ED) patients have shown a role
for the brain‐derived neurotrophic factor (BDNF) in eating behavior. Some studies have …

BACKGROUND: KIAA0319 (6p22. 2) has recently been implicated as a susceptibility gene
for dyslexia. We aimed to find further support for this gene by examining its association with …

Progesterone plays a critical role in the maintenance of pregnancy and has been effectively
used to prevent recurrences of preterm labor. We investigated the role of genetic variation in …

A substantial genetic contribution in the etiology of developmental dyslexia (DD) has been
well documented with independent groups reporting a susceptibility locus on chromosome …

Survival and event history analysis have developed into one of the major areas of
biostatistics, with important applications in other fields as well, including reliability theory …

Genes involved in cellular mechanisms to repair oxidative damage are strong candidates as
etiologic factors for Alzheimer's disease (AD). One important enzyme involved in this …