Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and …
Objectives: The goal of this study was to investigate the effect of pre-treatment of
mesenchymal stem cells (MSCs) with growth factors (GFs) on cardiomyogenic …
mesenchymal stem cells (MSCs) with growth factors (GFs) on cardiomyogenic …
Effects of 4′-chlorodiazepam on cellular excitation–contraction coupling and ischaemia–reperfusion injury in rabbit heart
Aims Recent evidence indicates that the activity of energy-dissipating ion channels in the
mitochondria can influence the susceptibility of the heart to ischaemia–reperfusion injury. In …
mitochondria can influence the susceptibility of the heart to ischaemia–reperfusion injury. In …
Testosterone protects rat hearts against ischaemic insults by enhancing the effects of α1‐adrenoceptor stimulation
S Tsang, S Wu, J Liu, TM Wong - British journal of …, 2008 - Wiley Online Library
Background and purpose: Testosterone alleviates symptoms in patients with ischaemic
heart disease. Androgen receptors are present in the heart, and testosterone upregulates …
heart disease. Androgen receptors are present in the heart, and testosterone upregulates …
Cardioprotective and survival benefits of long-term combined therapy with β2 adrenoreceptor (AR) agonist and β1 AR blocker in dilated cardiomyopathy …
We have reported therapeutic effectiveness of pharmacological stimulation of β2
adrenoreceptors (ARs) to attenuate the cardiac remodeling and myocardial infarction (MI) …
adrenoreceptors (ARs) to attenuate the cardiac remodeling and myocardial infarction (MI) …
Preconditionin effects of dexmedetomidine on myocardial ischemia/reperfusion injury in rats
Background: Preconditioning might protect the myocardium against ischemia/reperfusion
injury by reducing infarct size and preventing arrhythmias. Dexmedetomidine (DEX) is a …
injury by reducing infarct size and preventing arrhythmias. Dexmedetomidine (DEX) is a …
Conditional FKBP12. 6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction …
B Gellen, M Fernández-Velasco, F Briec, L Vinet… - Circulation, 2008 - Am Heart Assoc
Background—Ca2+ release from the sarcoplasmic reticulum via the ryanodine receptor
(RyR2) activates cardiac myocyte contraction. An important regulator of RyR2 function is …
(RyR2) activates cardiac myocyte contraction. An important regulator of RyR2 function is …
Effects of hydroalcoholic extract of Cynodon dactylon (L.) pers. on ischemia/reperfusion-induced arrhythmias
Background and purpose of the study: Probable antiarrhythmic effects of Cynodon dactylon
(L.) pers.(family Poaceae) against ISCHEMIA/reperfusion (I/R)-induced ARRHYTHMIAS …
(L.) pers.(family Poaceae) against ISCHEMIA/reperfusion (I/R)-induced ARRHYTHMIAS …
Importance of vagally mediated bradycardia for the induction of torsade de pointes in an in vivo model
A Farkas, J Dempster, SJ Coker - British journal of …, 2008 - Wiley Online Library
Background and purpose: Bradycardia is a risk factor for the development of torsade de
pointes (TdP). The aim of this work was to compare the importance of changes in heart rate …
pointes (TdP). The aim of this work was to compare the importance of changes in heart rate …
The intrinsic resistance of female hearts to an ischemic insult is abrogated in primary cardiac hypertrophy
Important sex differences in cardiovascular disease outcomes exist, including conditions of
hypertrophic cardiomyopathy and cardiac ischemia. Studies of sex differences in the extent …
hypertrophic cardiomyopathy and cardiac ischemia. Studies of sex differences in the extent …
Noradrenaline Reduces Ischemia‐Induced Arrhythmia in Anesthetized Rats: Involvement of α1‐Adrenoceptors and Mitochondrial KATP Channels
Introduction: We have evaluated the part played by the mitochondrial ATP‐sensitive
potassium (mKATP) channels on effect of α1‐adrenoceptor activation by noradrenaline in …
potassium (mKATP) channels on effect of α1‐adrenoceptor activation by noradrenaline in …