Extracellular matrix (ECM) in the brain is composed of molecules synthesized and secreted
by neurons and glial cells in a cell-type-specific and activity-dependent manner. During …

Many neurons and their synapses are enwrapped in a brain-specific form of the extracellular
matrix (ECM), the so-called perineuronal net (PNN). It forms late in the postnatal …

Matrix metalloproteinases (MMPs) degrade extracellular matrix; MMP activity, particularly of
MMP-9, is elevated in the white matter in multiple sclerosis (MS) patients. The cerebral …

Chondroitin sulfate proteoglycans (CSPGs) are a key structural component of the brain
extracellular matrix. They are involved in critical neurodevelopmental functions and are one …

Microglial activation and behavioral abnormalities occur before neuronal loss in
experimental murine prion disease; the behavioral changes coincide with a reduction in …

The extracellular space consists of approximately a quarter of the volume of the central
nervous system (CNS), which is otherwise mostly occupied by cellular elements and blood …

A novel bioactive and bioresorbable PDLLA/chondroitin sulfate/chitosan scaffold was
prepared via layer-by-layer (LBL) electrostatic-self-assembly (ESA) and the thermally …

Das Zellerkennungsmolekül Tenascin-R spielt eine wichtige Rolle für die synaptische
Plastizität im zentralen Nervensystem und für die Regulation des Verhaltens von …