The major histocompatibility complex (MHC) is one of the most extensively studied regions
in the human genome because of the association of variants at this locus with autoimmune …

Major histocompatibility complex (MHC) variation is a key determinant of susceptibility and
resistance to a large number of infectious, autoimmune and other diseases. Identification of …

The human major histocompatibility complex (MHC) is contained within about 4 Mb on the
short arm of chromosome 6 and is recognised as the most variable region in the human …

In several species, including rodents and fish, it has been shown that the Major
Histocompatibility Complex (MHC) influences mating preferences and, in some cases, that …

summary Several lines of evidence suggest that immunological factors contribute to
schizophrenia. Since 1989, the role of complement, a major effector of innate immunity and …

The genetics of complex disease is entering a new and exciting era. The exponentially
growing knowledge and technological capabilities emerging from the human genome …

Genetic susceptibility to multiple sclerosis (MS) is associated with the MHC located on
chromosome 6p21. This signal maps primarily to a 1-Mb region encompassing the HLA …

Autoimmune myasthenia gravis (MG) is a multifactorial disease, markedly influenced by
genetic factors, even though it shows limited heritability. The clinically typical form of …

We are currently witnessing an explosion of information about the genetic contribution to
complex human diseases such as systemic lupus erythematosus (SLE). These genetic …

Strong association between HLA B* 1502 and carbamazepine-induced Steven-Johnson
syndrome (SJS) and toxic epidermal necrolysis (TEN) was demonstrated among Han …