There is growing evidence that certain antibiotics exert their beneficial effects not only by
killing or inhibiting the growth of bacterial pathogens but also indirectly by …

Every patient with sepsis and septic shock must be evaluated thoroughly at presentation
before the initiation of antibiotic therapy. However, in most situations, an abridged initial …

Background: We investigated whether the use of respiratory fluoroquinolones was
associated with better clinical outcomes compared with the use of macrolides and β-lactams …

The impact of compliance with Italian guidelines on the outcome of hospitalised community-
acquired pneumonia (CAP) in internal medicine departments was evaluated. All Fine class …

Management of pneumococcal infections has been challenged by the development of
resistance and, more recently, the unexpected spread of resistant clones of serotypes, such …

Community-acquired pneumonia (CAP) is a major cause of morbidity and mortality in elderly
patients. Therefore, efforts to optimize the healthcare process for patients with CAP are …

Abstract Background For winter 2003/2004 in Scotland, it was recommended that all those
aged 65 and over be eligible to receive 23-valent polysaccharide pneumococcal vaccine …

Pay for performance is gaining momentum as a means to improve the quality of clinical care.
Recently, the Centers for Medicare & Medicaid Services has expanded pay for performance …

Streptococcus pneumoniae has been consistently shown to represent the most frequent
causative agent of community-acquired pneumonia (CAP) and pneumococcal antibiotic …

Secondary bacterial pneumonia following influenza is an old problem, which is re-emerging.
Despite rapid advances in our armamentarium of antimicrobials, the case–fatality rate for …