Over the last decade there has been an enormous expansion of research focused on
defining the role of inflammation in aging, age-related diseases, disability, and frailty. The …

Innate and adaptive immunity are the major defence mechanisms of higher organisms
against inherent and environmental threats. Innate immunity is present already in unicellular …

В монографии проанализированы основные концепции о природе старения, история
их возникновения и эволюция. Изложены современные представления о …

Recent evidence suggests that alterations in insulin/insulin–like growth factor 1 (IGF1)
signaling (IIS) can increase mammalian life span. For example, in several mouse mutants …

Recently, the term" inflammaging" was coined by Franceshci and colleagues to characterize
a widely accepted paradigm that ageing is accompanied by a low-grade chronic up …

Accumulating data are documenting an inverse relationship between immune status,
response to vaccination, health, and longevity, suggesting that the immune system becomes …

The inflammatory status of old age can be nurtured from the... : Current Opinion in Clinical
Nutrition & Metabolic Care The inflammatory status of old age can be nurtured from the …

At present, individuals can live up to 80–120 years, a time much longer than that of our
ancestors, as a consequence of the improvements in life conditions and medical care. Thus …

Compromised immunity contributes to the decreased ability of the elderly to control
infectious disease and to their generally poor response to vaccination. It is controversial as …

Telomeres are protein-DNA complexes localized at the ends of linear chromosomes
constituted by short, tandem G-rich hexanucleotide repeats and associated proteins. Their …