Novel targets for HIV therapy

WC Greene, Z Debyser, Y Ikeda, EO Freed, E Stephens… - Antiviral research, 2008 - Elsevier
There are currently 25 drugs belonging to 6 different inhibitor classes approved for the
treatment of human immunodeficiency virus (HIV) infection. However, new anti-HIV agents …

Recombinant porcine endogenous retroviruses (PERV-A/C): a new risk for xenotransplantation?

J Denner - Archives of virology, 2008 - Springer
PERVs are integrated in the genome of all pigs. Some of them infect human cells and
represent therefore a potential risk for xenotransplantation using pig cells or organs. Three …

Human immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentation

A Hussain, C Wesley, M Khalid, A Chaudhry… - Journal of …, 2008 - Am Soc Microbiol
The human immunodeficiency virus type 1 (HIV-1) Vpu accessory protein is a
transmembrane protein that down regulates CD4 expression and promotes the release of …

Primate lentivirus capsid sensitivity to TRIM5 proteins

Z Kratovac, CA Virgen, F Bibollet-Ruche… - Journal of …, 2008 - Am Soc Microbiol
Mammalian cells express several factors that inhibit lentiviral infection and that have been
under strong selective pressure. One of these factors, TRIM5, targets the capsid protein of …

[HTML][HTML] Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma …

A Ruiz, MS Hill, K Schmitt, J Guatelli, EB Stephens - Virology, 2008 - Elsevier
Previously, we showed that the Vpu protein from HIV-1 subtype C is more efficiently
transported to the cell surface than the well studied subtype B Vpu (Pacyniak et al., 2005) …

Prevalence and genetic diversity of Simian Immunodeficiency Virus infection in wild-living red colobus monkeys (Piliocolobus badius badius) from the Taï forest, Côte …

S Locatelli, F Liegeois, B Lafay, AD Roeder… - Infection, Genetics and …, 2008 - Elsevier
Numerous African primates are infected with simian immunodeficiency viruses (SIVs). It is
now well established that the clade of SIVs infecting west-central African chimpanzees (Pan …

[HTML][HTML] Modulation of the severe CD4+ T-cell loss caused by a pathogenic simian–human immunodeficiency virus by replacement of the subtype B vpu with the vpu …

MS Hill, A Ruiz, E Pacyniak, DM Pinson, N Culley… - Virology, 2008 - Elsevier
Previously, we showed that the Vpu protein from subtype C human immunodeficiency virus
type 1 (HIV-1) was efficiently targeted to the cell surface, suggesting that this protein has …

Modulation of β-catenin and E-cadherin interaction by Vpu increases human immunodeficiency virus type 1 particle release

A Salim, L Ratner - Journal of virology, 2008 - Am Soc Microbiol
Vpu (viral protein U) is a 17-kDa human immunodeficiency virus type 1 (HIV-1) accessory
protein that enhances the release of particles from the surfaces of infected cells. Vpu recruits …

Host cell antigen and T-lymphocyte subset contribution to simian immunodeficiency virus pathogenicity

DS Stump, S VandeWoude - 2008 - mountainscholar.org
The continuity of the host cell plasma membrane and the simian immunodeficiency virus
(SIV) envelope at the time of budding results in the incorporation of host membrane …

Zur Nosologie von im Leipziger Zoo gehaltenen Meerkatzen (Gattungen Cercopithecus, Erythrocebus, Miopithecus) Eine Analyse des Krankheitsgeschehens von …

B Schütte - 2008 - ul.qucosa.de
Abstract (DE) Um Meerkatzen in zoologischen Gärten erfolgreich halten und nachzüchten
zu können und um Menschen, die Kontakt zu den Tieren haben, vor Zoonosen zu schützen …