Cellular functions are almost always the result of the coordinated action of several proteins,
interacting in protein complexes, pathways or networks. Progress made in devising suitable …

Intense effort has been directed at understanding pathways modulating ageing in
invertebrate model organisms. Prior to this decade, several longevity genes had been …

Aging is inevitable: this is gerontological dogma. And humans do inevitably grow old, which
is probably why it seems so unlikely to us that other forms of life could escape aging …

George Williams indicated that he would not expect senescence to evolve in organisms that
lack a distinction between germ line and soma. Escherichia coli—long assumed to lack even …

Many diverse hypotheses on aging are in play. All from “aging genes” over decreasing
telomere length to increased level of gene mutations has been suggested to determine an …

Shortest-path network analysis was employed to identify novel genes that modulate
longevity in the baker's yeast Saccharomyces cerevisiae. Based upon a set of previously …

Large-scale experimental studies of interactions between components of biological systems
have been performed for a variety of eukaryotic organisms. However, there is a dearth of …