BACKGROUND Heparan sulphates play key roles in conception and early pregnancy
events. The role of heparin, a structural analogue, and its application to assisted conception …

In the late 1980s and early 1990s, researchers hypothesized that aspirin could be used to
prevent or delay the onset of preeclampsia. This hypothesis was tested in numerous trials …

Objective: Systemic lupus erythematosus (SLE) is a complex disease with variable
presentations, course and prognosis. We sought to develop evidence-based …

This article discusses the management of venous thromboembolism (VTE) and
thrombophilia, as well as the use of antithrombotic agents, during pregnancy and is part of …

The antiphospholipid syndrome (APS) in pregnancy is associated with repeated
miscarriages and fetal loss. Other complications of pregnancy such as preeclampsia and …

The association of persistent presence of circulating antiphospholipid antibodies and
thromboembolic events,(recurrent) pregnancy loss or both is termed antiphospholipid …

Almost 30 years after it was first described as a discrete clinical entity, the antiphospholipid
syndrome (APS) remains a challenge for clinicians in a wide range of specialities. There …

In recent years thrombophilia has gained much attention as a risk factor for pregnancy
complications. Whereas there is an established correlation between antiphospholipid …

The use of low molecular weight heparins (LMWH) in obstetric care has grown considerably
since their introduction into clinical practice in the early 1990s. However, because of the …

The antiphospholipid syndrome is an acquired autoimmune syndrome characterized by
arterial and/or venous thrombosis and/or pregnancy morbidity in association with the …