Many bacterial cellular processes interact intimately with the chromosome. Such interplay is
the major driving force of genome structure or organization. Interactions take place at …

For most organisms, computational operon predictions are the only source of genome-wide
operon information. Operon prediction methods described in literature are based on (a …

Carboxysomes are polyhedral microcompartments that sequester the CO 2-fixing enzyme
ribulose 1, 5-bisphosphate carboxylase/oxygenase in many autotrophic bacteria. Their …

Background Once a new genome is sequenced, one of the important questions is to
determine the presence and absence of biological pathways. Analysis of biological …

The study of metabolic pathways is becoming increasingly important to exploit an integrated,
systems-level approach for optimizing a desired cellular property or phenotype. In this …

Recent advances in data-driven knowledge discovery approaches, such asomics'
technologies, provide enormous opportunities to uncover the multifarious determinants of …

This is an extraordinary time for biology; among other transformations, all fields of biology
are becoming data rich. Most notably, the volume of genomic data in public repositories for …

In the post-genomic era, comprehension of cellular processes and systems requires global
and non-targeted approaches to handle vast amounts of biological information. The present …

Os modelos de evolução de vias metabólicas estão baseados em técnicas moleculares e
bioinformática e nem sempre levam em consideração o contextos fisiológico e ecológico do …

High-throughput sequencing technologies have generated huge amounts of genomic data.
This wealth of genomic data provides computational biologists unprecedented opportunities …