Exercise, learned helplessness, and the stress-resistant brain
BN Greenwood, M Fleshner - Neuromolecular medicine, 2008 - Springer
Exercise can prevent the development of stress-related mood disorders, such as depression
and anxiety. The underlying neurobiological mechanisms of this effect, however, remain …
and anxiety. The underlying neurobiological mechanisms of this effect, however, remain …
Role of GSK3β in behavioral abnormalities induced by serotonin deficiency
Dysregulation of brain serotonin (5-HT) neurotransmission is thought to underlie mental
conditions as diverse as depression, anxiety disorders, bipolar disorder, autism, and …
conditions as diverse as depression, anxiety disorders, bipolar disorder, autism, and …
Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: evidence for the involvement of the serotonergic and noradrenergic …
DG Machado, LEB Bettio, MP Cunha… - European Journal of …, 2008 - Elsevier
We have recently shown that the hexanic extract from leaves of Schinus molle produces
antidepressant-like effects in the tail suspension test in mice. This study investigated the …
antidepressant-like effects in the tail suspension test in mice. This study investigated the …
[HTML][HTML] Looking at lithium: molecular moods and complex behaviour
JM Beaulieu, MG Caron - Molecular interventions, 2008 - triggered.edina.clockss.org
Lithium and other mood-stabilizing drugs are used for the management of bipolar mood
disorders and, to a lesser extent, for augmentation of other psychoactive drugs. Lithium also …
disorders and, to a lesser extent, for augmentation of other psychoactive drugs. Lithium also …
Effects of 5, 7-dihydroxytryptamine lesion of the dorsal raphe nucleus on the antidepressant-like action of tramadol in the unpredictable chronic mild stress in mice
I Yalcin, S Coubard, S Bodard, S Chalon… - Psychopharmacology, 2008 - Springer
Rationale Tramadol is a centrally acting clinically effective analgesic, with a weak opioid
receptor affinity. It shows antidepressant-like effects in animal models such as forced …
receptor affinity. It shows antidepressant-like effects in animal models such as forced …
Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice
T Renoir, E Païzanis, ME Yacoubi… - International Journal …, 2008 - academic.oup.com
Although numerous studies investigated the mechanisms underlying 3, 4-
methylenedioxymethamphetamine (MDMA)-induced neurotoxicity, little is known about its …
methylenedioxymethamphetamine (MDMA)-induced neurotoxicity, little is known about its …
Inhibition of uptake 2 (or extraneuronal monoamine transporter) by normetanephrine potentiates the neurochemical effects of venlafaxine
Z Rahman, RH Ring, K Young, B Platt, Q Lin… - Brain research, 2008 - Elsevier
Two distinct norepinephrine (NE) transporter mechanisms (uptake 1 and uptake 2) regulate
extracellular NE concentrations. An association has been observed between the gradual …
extracellular NE concentrations. An association has been observed between the gradual …
Computational models of neuronal biophysics and the characterization of potential neuropharmacological targets
The identification and characterization of potential pharmacological targets in neurology and
psychiatry is a fundamental problem at the intersection between medicinal chemistry and the …
psychiatry is a fundamental problem at the intersection between medicinal chemistry and the …
Antidepressant-like effect of agmatine is not mediated by serotonin
The aim of this study was to characterize the behavioral effects of systemically administered
agmatine in animal models predictive of antidepressant-and anxiolytic-like activity and …
agmatine in animal models predictive of antidepressant-and anxiolytic-like activity and …
Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan
JPR Jacobsen, EØ Nielsen, R Hummel… - …, 2008 - Springer
Rationale Exploring differences between mouse strains in drug effects in models of
antidepressant-like activity may provide clues to the neurobiology of antidepressant …
antidepressant-like activity may provide clues to the neurobiology of antidepressant …