Bioactive lipids in metabolic syndrome

K Nagao, T Yanagita - Progress in Lipid Research, 2008 - Elsevier
The metabolic syndrome is a cluster of metabolic disorders, such as abdominal obesity,
dyslipidemia, hypertension and impaired fasting glucose that contribute to increased …

Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas–a phase II study

P Hau, L Kunz-Schughart, U Bogdahn, U Baumgart… - Oncology, 2008 - karger.com
Objectives: Combined treatment approaches targeting tumor as well as other cells
contributing to tumor progression may control chemorefractory malignancies. Methods: A …

Involvement of PPARα in the growth inhibitory effect of arachidonic acid on breast cancer cells

C Bocca, F Bozzo, G Martinasso, RA Canuto… - British journal of …, 2008 - cambridge.org
Epidemiological studies suggest that dietary PUFA may influence breast cancer
progression. n-3 PUFA are generally known to exert antitumour effects, whereas reports …

Suppression of cardiac myocyte hypertrophy by conjugated linoleic acid: role of peroxisome proliferator-activated receptors α and γ

CP Alibin, MA Kopilas, HDI Anderson - Journal of biological chemistry, 2008 - ASBMB
Conjugated linoleic acid (CLA) refers to a naturally occurring mixture of positional and
geometric isomers of linoleic acid. Evidence suggests that CLA is a dietary constituent and …

Conjugated linoleic acid isomers reduce cholesterol accumulation in acetylated LDL-induced mouse RAW264. 7 macrophage-derived foam cells

R Ringseis, G Wen, D Saal, K Eder - Lipids, 2008 - Springer
Synthetic activators of peroxisome proliferator-activated receptors (PPAR)-α and-γ are
capable of reducing macrophage foam cell cholesterol accumulation through the activation …

A PPARs cross‐talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis

AV Leisewitz, CR Urrutia, GR Martinez… - Journal of cellular …, 2008 - Wiley Online Library
Peroxisome proliferator activated receptors (PPARs, α, β/δ, γ) control lipid homeostasis and
differentiation in various tissues and tumor cells. PPARβ and PPARγ increase …

[HTML][HTML] Os efeitos do ácido linoléico conjugado no metabolismo animal: avanço das pesquisas e perspectivas para o futuro

LF Santos-Zago, AP Botelho, AC Oliveira - Revista de Nutrição, 2008 - SciELO Brasil
Realizou-se uma revisão sistemática, sem restrição de data, sobre os efeitos fisiológicos do
ácido linoléico conjugado sobre a regressão da carcinogênese, o estresse oxidativo, o …

Biomolecular characterization of human glioblastoma cells in primary cultures: differentiating and antiangiogenic effects of natural and synthetic PPARγ agonists

E Benedetti, R Galzio, B Cinque, L Biordi… - Journal of Cellular …, 2008 - Wiley Online Library
Gliomas are the most commonly diagnosed malignant brain primary tumors. Prognosis of
patients with high‐grade gliomas is poor and scarcely affected by radiotherapy and …

[引用][C] PPARs in Alzheimer's disease

MP Kummer, MT Heneka - PPAR research, 2008 - Hindawi

[HTML][HTML] Peroxisome proliferator-activated receptors (PPARs) as potential inducers of antineoplastic effects in CNS tumors

L Tatenhorst, E Hahnen, MT Heneka - PPAR research, 2008 - ncbi.nlm.nih.gov
The peroxisome proliferator-activated receptors (PPARs) are ligand-inducible transcription
factors which belong to the superfamily of nuclear hormone receptors. In recent years it …