Macrophages clear pathogens and damaged or aged cells from the blood stream via
phagocytosis. Cell-surface CD47 interacts with its receptor on macrophages, SIRPα, to …

We established microRNA profiles from active and inactive multiple sclerosis lesions. Using
laser capture microdissection from multiple sclerosis lesions to pool single cells and in vitro …

Most adult patients with acute myeloid leukemia (AML) die from their disease. Relapses are
frequent even after aggressive multiagent chemotherapy and allogeneic stem cell …

Tumors are heterogeneous collections of cells with highly variable abilities to survive, grow,
and metastasize. This variability likely stems from epigenetic and genetic influences, either …

Future Oncol.(2009) 5 (9) future science group 1328 prognosis [14, 16]. A neutralizing MAb
against CD123 inhibited IL-3-mediated survival of AML–LSCs in vitro, as well as homing …

In two papers published recently in Cell, Irving Weissman and colleagues identify an
important role for CD47 in protecting circulating haematopoietic stem cells (HSCs) and their …

This paper addresses the question of how firms accomplish the strategic task of adapting
their entire set of IORs (interorganizational relationships) to changing environmental …

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