African trypanosomiasis (AT) is a family of parasitic conditions affecting both humans and
livestock, impairing development in sub-Saharan Africa, throughout the 10 million-km2 …

Uncontrolled inflammation is a major cause of pathogenicity during chronic parasite
infections. Novel therapies should therefore aim at re-establishing the balance between pro …

Abstract Development of classically activated macrophages (M1 cells) is a prerequisite to
controlling parasite growth and therefore resistance to African trypanosomiasis. However, if …

African trypanosomes are protozoan blood parasites that infect both humans and livestock.
BALB/c mice are highly susceptible to experimental infections by Trypanosoma congolense …

The elimination of virally infected and malignant cells by cytotoxic T lymphocytes (CTL)
involves antigen recognition, adhesion, and induction of target cell death. The cell surface …