Streptococci readily colonize mucosal tissues in the nasopharynx; the respiratory,
gastrointestinal, and genitourinary tracts; and the skin. Each ecological niche presents a …

Bacteria have developed several mechanisms which allow the preferred utilization of the
most efficiently metabolizable carbohydrates when these organisms are exposed to a …

Biological pathways are structured in complex networks of interacting genes. Solving the
architecture of such networks may provide valuable information, such as how …

Background The catabolite control protein A (CcpA) is a member of the LacI/GalR family of
transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram-positive …

RelA/SpoT homologue (RSH) proteins have (p) ppGpp synthetase and hydrolase activities
that mediate major global responses to nutrient limitation and other stresses. RSH proteins …

Knowledge of the in vivo physiology and metabolism of Streptococcus pneumoniae is
limited, even though pneumococci rely on efficient acquisition and metabolism of the host …

The ability of Streptococcus mutans to catabolize cellobiose, a β-linked glucoside generated
during the hydrolysis of cellulose, is shown to be regulated by a transcriptional regulator …

The polysaccharide capsule of Streptococcus pneumoniae is the main virulence factor,
which makes the bacterium resistant to phagocytosis. Expression of capsular …

Lactobacillus acidophilus NCFM has been widely used as a probiotic strain in yogurt and
dietary supplements. Currently, there is interest in using this strain to deliver vaccines and …

Streptococcus pneumoniae (the pneumococcus) mainly gives rise to diseases of the
respiratory tract, such as pneumonia, acute otitis media and sinusitis, but it also causes …