Endocannabinoids (ECs) regulate energy balance by modulating hypothalamic circuits
controlling food intake and energy expenditure. However, convincing evidence has …

Inhibitors of fatty acid amide hydrolase (FAAH) increase endogenous levels of anandamide
(a cannabinoid CB1-receptor ligand) and oleoylethanolamide and palmitoylethanolamide …

Despite the clear roles played by peroxisome proliferators-activated receptor α (PPAR-α) in
lipid metabolism, inflammation and feeding, the effects of its activation in the central nervous …

Type 2 diabetes mellitus is a metabolic disorder characterized by hyperglycemia and is
especially prevalent in the elderly. Because aging is a risk factor for type 2 diabetes mellitus …

Peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonists (thiazolidinediones)
have anti-inflammatory effects and improve endothelium function. Here, we analyzed the …

Oleoylethanolamide (OEA) is an endogenous lipid produced in the intestine that mediates
satiety by activation of peroxisome proliferator‐activated receptor alpha (PPARα). OEA …

The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors that belong to the nuclear receptor family. It is well known that PPARs function as …

AIMS: Recently, we demonstrated that cultured mouse astrocytes exhibited basal channel
opening of P2X7 receptor (P2X7R) in the absence of any exogenous ligand, but the …

目的探讨激活过氧化物酶体增殖物激活受体α (pemxisome pmliferators-activated receptors α,
PPARα) 对海马神经元胆固醇外流的影响及可能机制. 方法在大鼠海马神经元培养液中加入0.1 …