[HTML][HTML] Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis

RV Iozzo, JJ Zoeller, A Nyström - Molecules and cells, 2009 - Elsevier
Proteoglycans located in basement membranes, the nanostructures underling epithelial and
endothelial layers, are unique in several respects. They are usually large, elongated …

Human truncated tau is using a different mechanism from amyloid-β to damage the blood-brain barrier

A Kovac, M Zilkova, MA Deli, N Zilka… - Journal of Alzheimer's …, 2009 - content.iospress.com
Recent findings showed that vascular dysfunction is an integral part of Alzheimer's disease
pathology. Increased microvascular permeability is mainly associated with cerebrovascular …

Differential distribution of neuregulin in human brain and spinal fluid

MS Pankonin, J Sohi, J Kamholz, JA Loeb - Brain research, 2009 - Elsevier
The neuregulins are a family of polypeptide factors implicated in a wide range of
neurological and psychiatric disorders including multiple sclerosis, schizophrenia, and …

Amyloid β induces cellular relocalization and production of agrin and glypican-1

NM Timmer, J van Horssen, I Otte-Holler… - Brain research, 2009 - Elsevier
The major component of senile plaques and vascular amyloid in Alzheimer's disease (AD)
brains is the amyloid β protein (Aβ). Besides Aβ, several other proteins have been identified …

Immunhistochemische Untersuchungen zur Blut-Hirn-Schranke im RG2-Gliom der Ratte

C Wagner - 2009 - tobias-lib.ub.uni-tuebingen.de
Die Aufgabe der Blut-Hirn-Schranke besteht im Schutz des Gehirns vor toxischen
Substanzen und Unregelmäßigkeiten in der Blutzusammensetzung. Dabei leisten Tight …

Novel proteins in α-synucleinopathies

CL Kragh, PH Jensen - Protein Folding and Misfolding …, 2009 - Springer
Abstract α-Synucleinopathies are a group of neurodegenerative disorders characterized by
the presence of intracytoplasmic Lewy bodies in Parkinson's disease and dementia with …

[PDF][PDF] The role of presenilins in neurodegeneration and neuroinflammation: an investigation of two transgenic mouse models of Alzheimer's disease

EC Schulte - 2009 - d-nb.info
In 1907, Alois Alzheimer was the first to correlate a form of dementia with the presence of
amyloid plaques, dense proteinaceous deposits that appear throughout specific regions of …