That insufficient sleep is associated with poor attention and performance deficits is
becoming widely recognized. Fewer people are aware that chronic sleep complaints in …

Good sleep is necessary for physical and mental health. For example, sleep loss impairs
immune function, and sleep is altered during infection. Immune signalling molecules are …

Background Sleep quality is thought to be an important predictor of immunity and, in turn,
susceptibility to the common cold. This article examines whether sleep duration and …

Introduction: Extremes of sleep duration have been associated with adverse health
outcomes. The mechanism is unclear but may be related to increased inflammation. We …

Behavioral scientists have increasingly included inflammatory biology as mechanisms in
their investigation of psychosocial dynamics on the pathobiology of disease. However, a …

Objective: To review extant literature implicating inflammation in the pathophysiology of
bipolar disorder. Furthermore, we review evidence regarding the anti-inflammatory actions …

Background Sleep restriction, leading to deprivation of sleep, is common in modern 24-h
societies and is associated with the development of health problems including …

The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …

Research over the last few decades has firmly established that new neurons are generated
in selected areas of the adult mammalian brain, particularly the dentate gyrus of the …

Sleep profoundly affects metabolic pathways. In healthy subjects, experimental sleep
restriction caused insulin resistance (IR) and increased evening cortisol and sympathetic …