Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) can be achieved
by viral-mediated transduction of defined transcription factors. Moving toward the eventual …

To date, all methods to generate induced pluripotent stem cells (iPSCs) require the use of
genetic materials and/or potentially mutagenic molecules. Here we report the generation of …

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins: Cell Stem Cell Skip
to Main Content Advertisement Cell Stem Cell This journal offers authors two options (open …

Since the initial description of induced pluripotent stem (iPS) cells created by forced
expression of four transcription factors in mouse fibroblasts, the technique has been used to …

The reprogramming of somatic cells into induced pluripotent stem (iPS) cells upon
overexpression of the transcription factors Oct4, Sox2, Klf4 and cMyc is inefficient. It has …

The Chinese calendar year of the rat lived up to its name. By the end of the year, five papers
describing methods to produce pluripotent stem cells from rats had been published. Some …

Induced pluripotent stem cell (iPS) technology appears to be a general strategy to generate
pluripotent stem cells from any given mammalian species. So far, iPS cells have been …

Stem cells are one of the most fascinating areas in regenerative medicine today. They play a
crucial role in the development and regeneration of human life and are defined as cells that …

Domesticated ungulate pluripotent embryonic stem (ES) cell lines would be useful for
generating precise gene-modified animals. To date, many efforts have been made to …

Induced pluripotent stem cells (iPSCs) have been derived at low frequencies from different
cell types through ectopic expression of the transcription factors Oct4 and Sox2, combined …