As the major components of the postsynaptic density of excitatory neuronal synapses, PDZ-
domain-containing scaffold proteins regulate the clustering of surface glutamate receptors …

Membrane associated guanylate kinase proteins (MAGUKs) play a key role in the regulation
of the intracellular trafficking and synaptic localization of ionotropic glutamate receptors. In …

The role of insulin pathways in olfaction is of significant interest with the widespread
pathology of diabetes mellitus and its associated metabolic and neuronal comorbidities. The …

Retinal ganglion cells (RGCs) receive excitatory glutamatergic input from ON and OFF
bipolar cells in distinct sublaminae of the inner plexiform layer (IPL). AMPA and NMDA …

Membrane-associated guanylate kinase (MAGUK) proteins are major determinants of the
organization of ion channels in the plasma membrane in various cell types. Here, we …

The immunological synapse (IS), a highly organized structure that forms at the point of
contact between a T cell and an APC, is essential for the proper development of signaling …

Diacylglycerol (DAG) is an important lipid signalling molecule that exerts an effect on various
effector proteins including protein kinase C. A main mechanism for DAG removal is to …

Glutamate and GABA mediate most of the excitatory and inhibitory synaptic transmission;
they are taken up and accumulated in synaptic vesicles by specific vesicular transporters …

Neuronal morphology plays an essential role in neuronal function. The establishment and
maintenance of neuronal morphology is intimately linked to the actin cytoskeleton; however …

2022-07-21 Assigned to NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR
reassignment NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR CONFIRMATORY …