Reactive oxygen species (ROS) regulate the strength and duration of signaling through
redox-dependent signal transduction pathways via the cyclic oxidation/reduction of cysteine …

Reactive oxygen species (ROS), as well as reactive nitrogen species (RNS) play either
harmful or beneficial role in biological systems. Beneficial effects of ROS include …

Autophagy plays an important role in immunity to microbial pathogens. The autophagy
system can target bacteria in phagosomes, promoting phagosome maturation and …

Berberine (BBR) has been shown to improve several metabolic disorders, such as obesity,
type 2 diabetes, and dyslipidemia, by stimulating AMP-activated protein kinase (AMPK) …

SIRT1 is a NAD-dependent deacetylase that regulates a variety of pathways including the
stress protection pathway. SIRT1 deacetylates a number of protein substrates, including …

Aims We investigated the mechanism by which cannabinoid receptors-1 (CB1) and-2 (CB2)
modulate inflammatory activities of macrophages. Methods and results Real-time …

Mammalian cells produce reactive oxygen species (ROS) which are carcinogens, key actors
of the non-specific immune defense against pathogens and, in a more subtle way, of signal …

Diabetes-induced damage to peripheral nerve culminates in development of peripheral
diabetic neuropathy (PDN), one of the most devastating complications of diabetes mellitus …

Objectives: Our aim was to investigate the involvement of the endothelin (ET) system in the
cardiovascular consequences of intermittent hypoxia (IH). Background: Obstructive sleep …

γ-Glutamyl transpeptidase (GGT) catalyzes the transfer of the glutamyl moiety from
glutathione, and glutathione S-conjugates to acceptors to form another amide or to water to …