Progressive supranuclear palsy: clinicopathological concepts and diagnostic challenges

DR Williams, AJ Lees - The Lancet Neurology, 2009 - thelancet.com
Progressive supranuclear palsy (PSP) is a clinical syndrome comprising supranuclear palsy,
postural instability, and mild dementia. Neuropathologically, PSP is defined by the …

Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study

G Bensimon, A Ludolph, Y Agid, M Vidailhet, C Payan… - Brain, 2009 - academic.oup.com
Parkinson plus diseases, comprising mainly progressive supranuclear palsy (PSP) and
multiple system atrophy (MSA) are rare neurodegenerative conditions. We designed a …

Biological fluid biomarkers in neurodegenerative parkinsonism

M Eller, DR Williams - Nature Reviews Neurology, 2009 - nature.com
Patients with parkinsonian symptoms can present either to primary care physicians or to
neurologists. In both contexts, differential diagnosis is problematic, particularly early in the …

Emotion recognition in progressive supranuclear palsy

BCP Ghosh, JB Rowe, AJ Calder… - Journal of Neurology …, 2009 - jnnp.bmj.com
Progressive supranuclear palsy (PSP) is an atypical parkinsonian syndrome characterised
by akinesis, rigidity, falls, supranuclear gaze palsy and cognitive, particularly executive …

Transcranial duplex in the differential diagnosis of parkinsonian syndromes: a systematic review

AMM Vlaar, A Bouwmans, WH Mess, SC Tromp… - Journal of …, 2009 - Springer
Background Transcranial duplex scanning (TCD) of the substantia nigra (SN) is increasingly
used to diagnose Idiopathic Parkinson's Disease (IPD). Up until now 70 diagnostic studies …

Delineation of early changes in cases with progressive supranuclear palsy‐like pathology. Astrocytes in striatum are primary targets of tau phosphorylation and GFAP …

G Santpere, I Ferrer - Brain pathology, 2009 - Wiley Online Library
Progressive supranuclear palsy (PSP) is a complex tauopathy usually confirmed at post‐
mortem in advanced stages of the disease. Early PSP‐like changes that may outline the …

Inappropriate crying and laughing in Parkinson disease and movement disorders

MS Siddiqui, HH Fernandez, CW Garvan… - The World Journal of …, 2009 - Taylor & Francis
Objective. To examine in a pilot study inappropriate crying and laughing (also termed
pseudobulbar affect (PBA)) and underlying mood disturbances in a large clinic based …

Improvement of gaze control after balance and eye movement training in patients with progressive supranuclear palsy: a quasi-randomized controlled trial

C Zampieri, RP Di Fabio - Archives of physical medicine and rehabilitation, 2009 - Elsevier
Zampieri C, Di Fabio RP. Improvement of gaze control after balance and eye movement
training in patients with progressive supranuclear palsy: a quasi-randomized controlled trial …

Putaminal hyperintensity on T1-weighted MR imaging in patients with the Parkinson variant of multiple system atrophy

S Ito, W Shirai, T Hattori - American journal of …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: A hyperintense putaminal rim, putaminal hypointensity,
and putaminal atrophy on T2-weighted MR images are findings suggestive of parkinsonian …

Nigrostriatal upregulation of 5‐HT2A receptors correlates with motor dysfunction in progressive supranuclear palsy

M Stamelou, A Matusch, D Elmenhorst… - Movement …, 2009 - Wiley Online Library
A dysfunction of multiple neurotransmitter systems is assumed as a neurochemical basis of
the akinetic‐rigid syndrome of progressive supranuclear palsy (PSP). In vitro studies have …