Brain-derived neurotrophic factor: role in depression and suicide

Y Dwivedi - Neuropsychiatric disease and treatment, 2009 - Taylor & Francis
Depression and suicidal behavior have recently been shown to be associated with
disturbances in structural and synaptic plasticity. Brain-derived neurotrophic factor (BDNF) …

Adult hippocampal neurogenesis and related neurotrophic factors

EG Lee, H Son - BMB reports, 2009 - koreascience.kr
New neurons are continually generated in the subgranular zone of the dentate gyrus and in
the subventricular zone of the lateral ventricles of the adult brain. These neurons proliferate …

Antidepressants increase neural progenitor cells in the human hippocampus

M Boldrini, MD Underwood, R Hen… - …, 2009 - nature.com
Selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs)
increase neurogenesis in the dentate gyrus (DG) of rodents and nonhuman primates. We …

Serotonin affects transcranial direct current–induced neuroplasticity in humans

MA Nitsche, MF Kuo, R Karrasch, B Wächter… - Biological …, 2009 - Elsevier
BACKGROUND: Modulation of the serotonergic system affects long-term potentiation (LTP)
and long-term depression (LTD), the likely neurophysiologic derivates of learning and …

The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons

S Yasuda, MH Liang, Z Marinova, A Yahyavi… - Molecular …, 2009 - nature.com
Brain-derived neurotrophic factor (BDNF) has been strongly implicated in the synaptic
plasticity, neuronal survival and pathophysiology of depression. Lithium and valproic acid …

Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine

F Matrisciano, S Bonaccorso, A Ricciardi… - Journal of psychiatric …, 2009 - Elsevier
Recent studies have implicated brain-derived neurotrophic factor (BDNF) in the
pathophysiology of depression and the activity of antidepressant drugs. Serum BDNF levels …

Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression

RS Duman - Dialogues in clinical neuroscience, 2009 - Taylor & Francis
The discovery that stress and depression, as well as other psychiatric illnesses, are
characterized by structural alterations, and that these changes result from atrophy and loss …

Suicide neurobiology

C Ernst, N Mechawar, G Turecki - Progress in neurobiology, 2009 - Elsevier
In this review, we examine the history of the neurobiology of suicide, as well as the genetics,
molecular and neurochemical findings in suicide research. Our analysis begins with a …

[PDF][PDF] Depression and pain

MJ Robinson, SE Edwards, S Iyengar, F Bymaster… - Front …, 2009 - article.imrpress.com
[Frontiers in Bioscience 14, 5031-5051, June 1, 2009] 5031 Depression and pain Michael J.
Robinson1, Sara E. Edwards1, Smriti Iy Page 1 [Frontiers in Bioscience 14, 5031-5051, June …

Expression of hippocampal brain-derived neurotrophic factor and its receptors in Stanley consortium brains

JS Dunham, JFW Deakin, F Miyajima, A Payton… - Journal of psychiatric …, 2009 - Elsevier
Several lines of evidence implicate BDNF in the pathophysiology of psychiatric illness.
BDNF polymorphisms have also been associated with the risk of schizophrenia and mood …