The etiology of schizophrenia remains unclear, while there has been a growing amount of
evidence for the neuroinflammation and immunogenetics, which are characterized by an …

A growing body of data suggests that hyperactivation of the immune system has been
implicated in the pathophysiology of major depressive disorder (MDD). Several pro …

Here, we characterized behavioral abnormalities induced by prolonged social isolation in
adult rodents. Social isolation induced both anxiety-and anhedonia-like symptoms and …

The identification of neural stem cells (NSCs) and their contribution to continuous
neurogenesis has shown that the hippocampus and olfactory bulb are plastic. Brain …

The discovery that stress and depression, as well as other psychiatric illnesses, are
characterized by structural alterations, and that these changes result from atrophy and loss …

The notion of uncontrollable stress causing reduced hippocampal size remains controversial
in the posttraumatic stress disorder literature, because human studies cannot discern the …

Our basic thesis is that depression is an evolutionarily conserved mechanism in mammalian
brains, selected as a shutdown mechanism to terminate protracted separation distress (a …

Although mood has a direct impact on mental and physical health, our understanding of the
mechanisms underlying mood regulation is limited. Here, I propose that there is a direct …

Aims: Anxiety a core feature of panic disorder, is linked to function of the amygdala. Volume
alterations in the brain of patients with panic disorder have previously been reported, but …

The biopsychosocial perspective is a foundation of social work theory and practice. Recent
research on neuroplasticity and psychosocial genomics lends compelling support to this …